Motif ID: FOX{I1,J2}.p2

Z-value: 0.560


Transcription factors associated with FOX{I1,J2}.p2:

Gene SymbolEntrez IDGene Name
FOXI1 2299 forkhead box I1
FOXJ2 55810 forkhead box J2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.p-valuePlot
FOXI1chr5_+_1695329000.232.7e-01Click!
FOXJ2chr12_+_81852410.019.6e-01Click!


Activity profile for motif FOX{I1,J2}.p2.

activity profile for motif FOX{I1,J2}.p2


Sorted Z-values histogram for motif FOX{I1,J2}.p2

Sorted Z-values for motif FOX{I1,J2}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of FOX{I1,J2}.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_+_84764048 1.103 NM_001010971
SAMD13
sterile alpha motif domain containing 13
chr19_-_14992166 1.057 NM_030901
OR7A17
olfactory receptor, family 7, subfamily A, member 17
chr19_-_4831711 1.011 NM_182919
TICAM1
toll-like receptor adaptor molecule 1
chr4_+_41614725 0.924 LIMCH1
LIM and calponin homology domains 1
chr1_+_84630575 0.835 NM_001242860
NM_001242861
PRKACB

protein kinase, cAMP-dependent, catalytic, beta

chr1_-_169703178 0.802 NM_000450
SELE
selectin E
chr12_+_27175501 0.775 MED21
mediator complex subunit 21
chr5_+_159614373 0.773 NM_001130958
FABP6
fatty acid binding protein 6, ileal
chr3_+_46448678 0.749 NM_003965
NM_001130910
CCRL2

chemokine (C-C motif) receptor-like 2

chr1_+_84768333 0.717 NM_001134664
SAMD13
sterile alpha motif domain containing 13
chr4_-_186577858 0.713 SORBS2
sorbin and SH3 domain containing 2
chr4_+_86749045 0.705 ARHGAP24
Rho GTPase activating protein 24
chr12_+_27175482 0.691 NM_004264
MED21
mediator complex subunit 21
chr9_+_127054246 0.686 NM_001166170
NM_001166171
NEK6

NIMA (never in mitosis gene a)-related kinase 6

chr1_+_84609941 0.656 NM_182948
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr8_-_22550708 0.638 NM_004430
EGR3
early growth response 3
chr4_-_186578122 0.637 NM_001145674
NM_001145675
SORBS2

sorbin and SH3 domain containing 2

chr3_-_187463474 0.564 NM_001706
BCL6
B-cell CLL/lymphoma 6
chr7_+_6617035 0.559 NM_001134387
NM_001134388
NM_001134389
NM_018106
ZDHHC4



zinc finger, DHHC-type containing 4



chr10_-_131762017 0.533 NM_001005463
EBF3
early B-cell factor 3
chr11_+_59522905 0.516 STX3
syntaxin 3
chr2_+_12857885 0.506 TRIB2
tribbles homolog 2 (Drosophila)
chr16_+_81812897 0.504 NM_002661
PLCG2
phospholipase C, gamma 2 (phosphatidylinositol-specific)
chr16_+_81812899 0.503 PLCG2
phospholipase C, gamma 2 (phosphatidylinositol-specific)
chr19_-_39826676 0.496 NM_004877
GMFG
glia maturation factor, gamma
chr19_+_14491920 0.481 NM_001025160
NM_001784
NM_078481
CD97


CD97 molecule


chr6_+_153019029 0.468 NM_025107
MYCT1
myc target 1
chr3_-_187454247 0.455 NM_001130845
BCL6
B-cell CLL/lymphoma 6
chr5_+_159436143 0.446 TTC1
tetratricopeptide repeat domain 1
chr1_-_151345156 0.443 NM_003944
SELENBP1
selenium binding protein 1
chr18_+_61554938 0.440 NM_001143818
NM_002575
SERPINB2

serpin peptidase inhibitor, clade B (ovalbumin), member 2

chr18_-_22930826 0.431


chr10_-_48806862 0.428 NM_001042357
NM_001042389
PTPN20B
PTPN20A
protein tyrosine phosphatase, non-receptor type 20B
protein tyrosine phosphatase, non-receptor type 20A
chr5_+_53751430 0.427 NM_006308
HSPB3
heat shock 27kDa protein 3
chr19_+_1026271 0.421 NM_004368
NM_201277
CNN2

calponin 2

chr14_-_81864726 0.421 NM_033104
STON2
stonin 2
chr19_+_45971249 0.418 NM_001114171
NM_006732
FOSB

FBJ murine osteosarcoma viral oncogene homolog B

chr12_-_48499840 0.416 SENP1
SUMO1/sentrin specific peptidase 1
chr21_-_27512668 0.406 NM_001136016
APP
amyloid beta (A4) precursor protein
chr10_-_46619935 0.401 NM_001042357
NM_001042389
PTPN20B
PTPN20A
protein tyrosine phosphatase, non-receptor type 20B
protein tyrosine phosphatase, non-receptor type 20A
chr3_+_109128836 0.400 NM_001145553
FLJ25363
uncharacterized LOC401082
chr2_+_162016926 0.398 NM_001199135
TANK
TRAF family member-associated NFKB activator
chr13_+_97928196 0.392 MBNL2
muscleblind-like 2 (Drosophila)
chr4_+_41614933 0.392 LIMCH1
LIM and calponin homology domains 1
chr12_-_105627182 0.391 NM_001251905
APPL2
adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2
chr2_+_201170603 0.390 NM_015535
SPATS2L
spermatogenesis associated, serine-rich 2-like
chr19_+_49375679 0.390 PPP1R15A
protein phosphatase 1, regulatory subunit 15A
chr19_+_49375677 0.378 PPP1R15A
protein phosphatase 1, regulatory subunit 15A
chr6_+_150263120 0.373 NM_025217
ULBP2
UL16 binding protein 2
chr7_+_77469446 0.373 NM_001127357
NM_001127359
NM_020432
PHTF2


putative homeodomain transcription factor 2


chr5_-_111312522 0.372 NM_001142474
NM_001142475
C5orf13

chromosome 5 open reading frame 13

chr2_-_188312872 0.372 NM_005795
CALCRL
calcitonin receptor-like
chr12_-_124068864 0.365


chr19_+_49375638 0.364 NM_014330
PPP1R15A
protein phosphatase 1, regulatory subunit 15A
chrX_-_24045302 0.363 NM_030624
KLHL15
kelch-like 15 (Drosophila)
chr4_+_74606222 0.362 NM_000584
IL8
interleukin 8
chr5_-_180076616 0.358 NM_002020
NM_182925
FLT4

fms-related tyrosine kinase 4

chr10_-_90712510 0.355 NM_001613
ACTA2
actin, alpha 2, smooth muscle, aorta
chr21_+_46293925 0.347


chr11_+_102188180 0.345 NM_001165
NM_182962
BIRC3

baculoviral IAP repeat containing 3

chr19_+_50879681 0.341 NM_007121
NR1H2
nuclear receptor subfamily 1, group H, member 2
chr9_+_131683173 0.338 NM_001100876
NM_174933
PHYHD1

phytanoyl-CoA dioxygenase domain containing 1

chr4_-_16900028 0.336 LDB2
LIM domain binding 2
chr9_+_79115548 0.336 NM_001097636
GCNT1
glucosaminyl (N-acetyl) transferase 1, core 2
chr11_-_64578765 0.330 NM_130803
NM_130804
MEN1

multiple endocrine neoplasia I

chr4_-_16900348 0.328 NM_001130834
NM_001290
LDB2

LIM domain binding 2

chr15_+_49462408 0.328 NM_002044
GALK2
galactokinase 2
chr4_-_16900256 0.326 LDB2
LIM domain binding 2
chr1_-_20445991 0.323 NM_012400
PLA2G2D
phospholipase A2, group IID
chr1_+_84630014 0.320 NM_001242857
NM_001242858
NM_001242859
PRKACB


protein kinase, cAMP-dependent, catalytic, beta


chr1_+_66798095 0.317 PDE4B
phosphodiesterase 4B, cAMP-specific
chr5_-_88179278 0.316 NM_001193350
NM_002397
MEF2C

myocyte enhancer factor 2C

chr17_-_16097882 0.316 NM_001190438
NM_001190440
NCOR1

nuclear receptor corepressor 1

chr6_+_26501448 0.312 NM_001732
BTN1A1
butyrophilin, subfamily 1, member A1
chr1_+_82266081 0.310 NM_012302
LPHN2
latrophilin 2
chr4_-_152096655 0.307 NM_001128924
SH3D19
SH3 domain containing 19
chr11_+_60552820 0.307 NM_206893
MS4A10
membrane-spanning 4-domains, subfamily A, member 10
chr5_-_997408 0.307 NM_001242737
LOC100506688
uncharacterized LOC100506688
chr9_+_120466607 0.307 TLR4
toll-like receptor 4
chr4_+_41614911 0.307 NM_001112719
NM_001112720
LIMCH1

LIM and calponin homology domains 1

chr12_-_10021932 0.302 CLEC2B
C-type lectin domain family 2, member B
chr15_-_55800431 0.301 NM_001033559
NM_001033560
NM_130810
DYX1C1


dyslexia susceptibility 1 candidate 1


chr12_-_9913415 0.296 NM_001781
CD69
CD69 molecule
chr19_-_5846465 0.293 FUT3
fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group)
chr19_-_22379752 0.289 NM_001001411
ZNF676
zinc finger protein 676
chr2_+_38155901 0.286 NM_001170792
FAM82A1
family with sequence similarity 82, member A1
chr1_+_101185195 0.279 NM_001078
NM_001199834
NM_080682
VCAM1


vascular cell adhesion molecule 1


chrX_-_8139307 0.279 NM_016378
VCX2
variable charge, X-linked 2
chr11_+_59522801 0.278 STX3
syntaxin 3
chr4_+_41361621 0.276 LIMCH1
LIM and calponin homology domains 1
chr2_+_201170795 0.275 NM_001100422
NM_001100424
NM_001100423
SPATS2L


spermatogenesis associated, serine-rich 2-like


chr19_+_36024313 0.273 NM_014364
GAPDHS
glyceraldehyde-3-phosphate dehydrogenase, spermatogenic
chr1_+_84630374 0.268 PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr8_-_80993009 0.267 NM_001025252
TPD52
tumor protein D52
chr21_-_35884503 0.260 KCNE1
potassium voltage-gated channel, Isk-related family, member 1
chr16_+_82068958 0.259 HSD17B2
hydroxysteroid (17-beta) dehydrogenase 2
chr7_+_44646189 0.258 OGDH
oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
chr8_+_74903563 0.255 NM_001195797
NM_015364
LY96

lymphocyte antigen 96

chr11_+_28131830 0.254 METTL15
methyltransferase like 15
chr5_+_159436155 0.253 NM_003314
TTC1
tetratricopeptide repeat domain 1
chr5_-_180076544 0.252 FLT4
fms-related tyrosine kinase 4
chr9_+_130860769 0.252 SLC25A25
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25
chr8_-_93111915 0.252 NM_001198628
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr2_+_132480063 0.251 NM_013310
C2orf27A
chromosome 2 open reading frame 27A
chr1_+_221053000 0.250 HLX
H2.0-like homeobox
chr15_-_60919642 0.250 NM_002943
NM_134260
RORA

RAR-related orphan receptor A

chr7_-_158611301 0.247 ESYT2
extended synaptotagmin-like protein 2
chr7_+_44646197 0.244 OGDH
oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
chr10_-_116286570 0.243 ABLIM1
actin binding LIM protein 1
chr7_-_150329285 0.242 GIMAP6
GTPase, IMAP family member 6
chr11_+_58390145 0.241 NM_000614
CNTF
ciliary neurotrophic factor
chr5_+_173472737 0.240 HMP19
HMP19 protein
chr9_+_130860816 0.239 NM_052901
NM_001006643
SLC25A25

solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25

chr16_+_82068910 0.238 HSD17B2
hydroxysteroid (17-beta) dehydrogenase 2
chr15_+_80390757 0.238 NM_001242919
ZFAND6
zinc finger, AN1-type domain 6
chr7_+_44646168 0.236 OGDH
oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
chr16_+_82068830 0.235 NM_002153
HSD17B2
hydroxysteroid (17-beta) dehydrogenase 2
chrX_+_135278912 0.235 NM_001159701
NM_001159699
FHL1

four and a half LIM domains 1

chr5_-_88119604 0.234 NM_001193348
NM_001193349
MEF2C

myocyte enhancer factor 2C

chr5_+_43609261 0.232 NNT
nicotinamide nucleotide transhydrogenase
chr15_+_42696957 0.231 NM_173089
NM_173090
CAPN3

calpain 3, (p94)

chr1_+_61869699 0.230 NFIA
nuclear factor I/A
chrX_+_135730335 0.226 NM_000074
CD40LG
CD40 ligand
chr1_+_66797775 0.226 NM_001037339
PDE4B
phosphodiesterase 4B, cAMP-specific
chr11_+_57529233 0.225 NM_001085458
NM_001085459
NM_001085460
NM_001085461
NM_001085462
NM_001085463
NM_001085464
NM_001085465
NM_001085466
NM_001085467
NM_001085468
NM_001085469
NM_001206883
NM_001206884
NM_001206885
NM_001206886
NM_001206887
NM_001206888
NM_001206889
NM_001206890
NM_001206891
NM_001331
CTNND1





















catenin (cadherin-associated protein), delta 1





















chr8_-_24772229 0.224 NEFM
neurofilament, medium polypeptide
chr2_-_191872322 0.224 STAT1
signal transducer and activator of transcription 1, 91kDa
chr16_+_10522724 0.222 NM_024997
ATF7IP2
activating transcription factor 7 interacting protein 2
chr11_-_17191287 0.221 NM_002645
PIK3C2A
phosphoinositide-3-kinase, class 2, alpha polypeptide
chr20_+_123230 0.220 NM_030931
DEFB126
defensin, beta 126
chr12_+_29302132 0.220 FAR2
fatty acyl CoA reductase 2
chr7_-_86688944 0.219 NM_001142749
KIAA1324L
KIAA1324-like
chr8_-_23261632 0.218 LOXL2
lysyl oxidase-like 2
chr19_+_41099071 0.218 NM_003573
LTBP4
latent transforming growth factor beta binding protein 4
chr15_+_78558522 0.218 NM_001130183
DNAJA4
DnaJ (Hsp40) homolog, subfamily A, member 4
chr2_-_44586854 0.215 NM_001042385
NM_001042386
PREPL

prolyl endopeptidase-like

chr15_-_74658498 0.214 NM_001099773
CYP11A1
cytochrome P450, family 11, subfamily A, polypeptide 1
chr16_+_20420854 0.214 NM_017888
ACSM5
acyl-CoA synthetase medium-chain family member 5
chr6_+_24357130 0.213 NM_181337
KAAG1
kidney associated antigen 1
chr19_-_11689765 0.212 NM_001111035
NM_001111036
ACP5

acid phosphatase 5, tartrate resistant

chr8_-_117023 0.211 NM_001005504
OR4F21
olfactory receptor, family 4, subfamily F, member 21
chr17_+_34087915 0.210 NM_145272
C17orf50
chromosome 17 open reading frame 50
chr17_-_29641068 0.210 EVI2B
ecotropic viral integration site 2B
chr1_+_155100304 0.208 NM_004428
NM_182685
EFNA1

ephrin-A1

chr11_+_128564130 0.207 FLI1
Friend leukemia virus integration 1
chr19_-_39322411 0.207 NM_001398
ECH1
enoyl CoA hydratase 1, peroxisomal
chr22_+_25423940 0.206 NM_001145206
KIAA1671
KIAA1671
chr10_+_127429031 0.205 C10orf137
chromosome 10 open reading frame 137
chr6_+_34205029 0.205 HMGA1
high mobility group AT-hook 1
chr5_-_111091947 0.205 NM_001142483
C5orf13
chromosome 5 open reading frame 13
chr2_+_233709104 0.204 GIGYF2
GRB10 interacting GYF protein 2
chr3_+_132036210 0.204 NM_001099
NM_001134194
ACPP

acid phosphatase, prostate

chr2_-_85108202 0.203 C2orf89
chromosome 2 open reading frame 89
chr19_-_54692132 0.203 MBOAT7
membrane bound O-acyltransferase domain containing 7
chr2_+_20646831 0.203 NM_004040
RHOB
ras homolog gene family, member B
chr12_-_53994783 0.202 NM_001130059
ATF7
activating transcription factor 7
chr2_+_33661392 0.199 NM_170672
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr5_+_42550181 0.199 NM_001242405
GHR
growth hormone receptor
chr20_+_30697291 0.199 NM_014742
TM9SF4
transmembrane 9 superfamily protein member 4
chr19_+_2819942 0.198 ZNF554
zinc finger protein 554
chr11_+_128563955 0.196 FLI1
Friend leukemia virus integration 1
chr2_+_210444154 0.196 MAP2
microtubule-associated protein 2
chr16_+_48278177 0.194 NM_031490
LONP2
lon peptidase 2, peroxisomal
chr2_-_239140214 0.194 LOC151174
uncharacterized LOC151174
chr13_+_53035227 0.191 CKAP2
cytoskeleton associated protein 2
chr6_-_13408368 0.190 NM_001242630
GFOD1
glucose-fructose oxidoreductase domain containing 1
chr19_+_52873169 0.190 NM_001145434
ZNF880
zinc finger protein 880
chr2_+_109204777 0.189 LIMS1
LIM and senescent cell antigen-like domains 1
chr5_+_61708565 0.189 NM_016338
IPO11
importin 11
chr2_+_219246751 0.189 NM_000578
SLC11A1
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1
chr2_+_33738941 0.186 NM_015376
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr2_+_233404436 0.185 NM_005199
CHRNG
cholinergic receptor, nicotinic, gamma
chrX_-_6453158 0.185 NM_016379
VCX2
VCX3A
variable charge, X-linked 2
variable charge, X-linked 3A
chr5_-_54281345 0.185 NM_001135604
NM_007036
ESM1

endothelial cell-specific molecule 1

chr17_+_38119225 0.184 NM_178171
GSDMA
gasdermin A
chr1_+_44064509 0.184 PTPRF
protein tyrosine phosphatase, receptor type, F
chr5_-_180076599 0.184 FLT4
fms-related tyrosine kinase 4
chr7_-_37488554 0.183 NM_014800
ELMO1
engulfment and cell motility 1
chr21_-_31869427 0.183 NM_181610
KRTAP19-4
keratin associated protein 19-4
chr14_-_20774089 0.183 TTC5
tetratricopeptide repeat domain 5
chr4_+_88754120 0.182 NM_001184695
NM_001184696
NM_001184697
NM_020203
MEPE



matrix extracellular phosphoglycoprotein



chr2_+_161993465 0.181 NM_004180
NM_133484
TANK

TRAF family member-associated NFKB activator

chr19_+_6464259 0.179 NM_139161
NM_174881
CRB3

crumbs homolog 3 (Drosophila)

chr20_+_30697512 0.179 TM9SF4
transmembrane 9 superfamily protein member 4
chr7_+_89783688 0.177 NM_012449
STEAP1
six transmembrane epithelial antigen of the prostate 1
chr2_+_203241044 0.176 NM_001204
BMPR2
bone morphogenetic protein receptor, type II (serine/threonine kinase)
chr13_+_36050885 0.176 NM_001204197
NBEA
neurobeachin
chr1_-_77685076 0.175 NM_005482
PIGK
phosphatidylinositol glycan anchor biosynthesis, class K
chr21_+_30517897 0.174 C21orf7
chromosome 21 open reading frame 7
chr6_-_132967141 0.174 NM_138327
TAAR1
trace amine associated receptor 1
chrX_+_118108595 0.174 NM_001031855
NM_024778
LONRF3

LON peptidase N-terminal domain and ring finger 3

chr2_-_32490688 0.174 NM_001199139
NM_021209
NLRC4

NLR family, CARD domain containing 4

chr16_-_3627353 0.173 NM_178844
NLRC3
NLR family, CARD domain containing 3
chr1_+_150337145 0.173 RPRD2
regulation of nuclear pre-mRNA domain containing 2
chr12_-_55378455 0.173 NM_001136030
KIAA0748
KIAA0748
chr18_+_33234532 0.173 NM_020474
GALNT1
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 1 (GalNAc-T1)
chr11_-_65793849 0.173 NM_053054
CATSPER1
cation channel, sperm associated 1
chr8_-_17752847 0.173 NM_147203
NM_201553
NM_004467
NM_201552
FGL1



fibrinogen-like 1



chr13_-_78493902 0.170 NM_001201397
EDNRB
endothelin receptor type B
chr7_+_89783789 0.170 STEAP1
six transmembrane epithelial antigen of the prostate 1

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.23 1.11e-02 GO:0032502 developmental process
1.23 4.15e-02 GO:0007275 multicellular organismal development

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.47 2.90e-03 GO:0044421 extracellular region part
1.47 3.00e-02 GO:0005615 extracellular space
1.90 3.05e-02 GO:0016323 basolateral plasma membrane

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.08 7.90e-03 GO:0005488 binding
1.13 1.12e-02 GO:0005515 protein binding